Universitair Medisch Centrum St Radboud 

UMC St RadboudResearch within the various sections of the Department is incorporated in three of the Faculty Research Institutes. Essentially, patient related research will be on ‘evidence based surgery’ in the Nijmegen Centre for Evidenced Based Practice (NCEBP).  Examples are Hernia repair, Treatment of pancreatitis, Value  of CT in trauma care and  Quality improvement of surgery for colorectal carcinoma. Oncology-related research, both clinical and preclinical, will be in the Institute for Oncology. Examples are Liver surgery and Peritoneal carcinomatosis. Preclinical research, with the exception of oncology-related topics, will be focussed within a theme ‘regenerative surgery’ in the Nijmegen Centre for Molecular Life Sciences (NCMLS). Examples are Repair of incisional and diaphragmatic hernias and Intestinal and peritoneal wound healing. Clinical Research Organisations (CRO) The Clinical Research Center Nijmegen (CRCN) would be a logical candidate to serve as the CRO for the intended Phase I/II study. The CRCN forms part of, and is located in, the UMC St Radboud. The CRCN is headed by Dr. Dyonne van Duren, formerly Managing Director and Owner of Dutch CRO Menox. The CRCN is well equipped and complies with all applicable regulatory requirements to support both early phase investigator-initiated studies and external sponsor-initiated trials directed at product registration. CDL The Central Animal Laboratory (CDL) offers expertise and facilities to conduct animal testing in behalf of biomedical research and education. Researchers at the University Medical Center St Radboud, the Radboud University and other institutes consult the CDL to get advice and support from planning upto and including the conduct of animal research. Although not having a formal GLP license, the CDL is perfectly suited for the performance of animal efficacy study meant for CE-marking/FDA-clearance. The CDL is staffed by well-trained personnel, and is equipped with advanced research apparatus. For example, it has a 7-Tesla fMRI-scanner to look at the tissues of small experimental animals with very high resolution. There is also the possibility of telemetry, where a transmitter implanted in the experimental animal allows the wireless monitoring of blood pressure, heart frequency, temperature, ECG and motor activities.


Radboud Universiteit Nijmegen

Radboud Universiteit NijmegenThe Department of Organic Chemistry is part of The Nijmegen Centre for Molecular Life Sciences (NCMLS), a leading multidisciplinary research school within the domain of molecular mechanisms of disease and particularly in the fields of molecular medicine, cell biology and translational research. The NCMLS accommodates research groups from the Radboud University Nijmegen Medical Centre and the Faculty of Science at the Radboud University Nijmegen. The major goal of the NCMLS is to generate basic knowledge from molecular medical research and to translate this knowledge into clinical application through the development of disease diagnostics and innovation in the treatment of patients. The multi-disciplinary approach to research in molecular life science is reflected in an established NCMLS Graduate School with a dedicated 2-year research honours MSc degree in Molecular Mechanisms of Disease and a follow-up 4-year PhD program. NCMLS innovation is advanced through a number of Technology Platforms, such as microscope imaging, genomics, proteomics and bioinformatics.